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Mississippi River Cruise

Mississippi River Cruises

Featured Cruises

Grand Heartland Cruise
Grand Heartland Cruise

15 day Grand Heartland Cruise sailing the Mississippi River from St. Paul, MN to New Orleans, LA aboard the Queen of the Mississippi. This epic two-week journey on the world's newest riverboat transports guests back into American History. Guests to visit 10 states in the most comfortable way possible. They will travel further thank even Huck Finn’s famous trip down the Mississippi - and experience northern fall foliage, southern hospitality, jazz, country, Graceland, barbeque, Cajun, Creole, the complete history of the Louisiana purchase, Civil War, and beginning of the Lewis and Clark expedition.

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Complete Mississippi River Cruise
Complete Mississippi River Cruise

22 day Complete Mississippi River Cruise sailing between New Orleans, LA to St. Paul aboard the American Eagle. This epic journey aboard the new American Eagle cruises the entire length of the Mississippi River from New Orleans, LA to St. Paul, MN. Visit 10 states in 22 days, even more than Huck Finn's famous trip down the Mississippi River, to experience a complete history of the western frontier.

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Lower Mississippi River Cruises

Roundtrip New Orleans aboard American Queen
Roundtrip New Orleans

5 or 9-day Roundtrip New Orleans Mississippi Cruise sailings aboard American Queen. These voyages feature classically iconic southern communities. Visit Oak Alley, LA one of the most photographed plantations. Tour St. Francisville, LA - a window to the past with over 140 buildings on the National Register. Stop in Baton Rouge, Louisiana’s capital – blending the past and the present.

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New Orleans to Memphis aboard American Queen
New Orleans to Memphis

8 or 9 day New Orleans to Memphis Mississippi River Cruises aboard the American Queen. Celebrate New Orleans’ unabashed and unapologetic joy in the fine restaurants and sidewalk cafes of the French Quarter, the jazz clubs lining Bourbon Street and the strolling musicians in Jackson Square. Music is also the heart and soul of Memphis - from Elvis’ inspiring Graceland to the blues joints of Beale Street. The city’s National Civil Rights Museum chronicles a long journey to freedom and the Stax Museum of American Soul Music records the rise of a beloved musical art form.

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Memphis to New Orleans aboard American Queen
Memphis to New Orleans

9 day Memphis to New Orleans Mississippi River Cruises sailing aboard the American Queen. The romance of the antebellum era and lively Cajun culture are found everywhere you turn. Sit in a rocking chair with a glass of sweet tea on the American Queen’s Front Porch of America and watch the essence of the South unfold around you.

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Memphis to St. Louis aboard American Queen
Memphis to New Orleans

8 day Memphis to St. Louis Mississippi River cruise sailing aboard the American Queen. Celebrate America's birthday and enjoy one of the nation’s largest fireworks displays in beautiful St. Louis. Enjoy a hotel night's stay and explore Memphis TN. Relive scenes out of the battle and siege of New Madrid, site of Cherokee Trail of Tears crossing.

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Roundtrip New Orleans aboard Queen of the Mississippi
Roundtrip New Orleans

8 day, 7 night roundtrip New Orleans cruising down the Mississippi River aboard the greatest paddlewheeler to ever grace the Mississippi River, the Queen of the Mississippi. This is a land of bayous and southern belles. From legendary jazz to the “grande dame” of all plantation homes, immerse yourself in the heritage of the Old South while cruising the Mississippi River. Discover romance in the quaint historic district of Natchez, or pay tribute to the blue and gray at the Vicksburg National Military and Park.

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New Orleans to Memphis aboard Queen of the Mississippi
Mississippi River - New Orleans to Memphis

8 day, 7 night New Orleans - Memphis Mississippi River cruise aboard the greatest paddlewheeler to ever grace the Mississippi River, the Queen of the Mississippi. Step ashore to explore historic Natchez, Civil-War era Vicksburg and Oak Alley, one of the Old South’s most legendary plantations.

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Memphis to St. Louis aboard Queen of the Mississippi
Memphis to St. Louis aboard Queen of the Mississippi

8 day, 7 night Memphis to St. Louis riverboat cruise on the Mississippi River to the heart and soul of America on American Cruise Lines’ brand new Mississippi Riverboat, Queen of the Mississippi. Explore Civil War and Underground Railroad sites, visit the most haunted city in America, and discover quintessential small-town America.

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St. Louis to New Orleans aboard Queen of the Mississippi
St. Louis to New Orleans aboard Queen of the Mississippi

8 day St. Louis - New Orleans Mississippi River cruise sailing aboard the Queen of the Mississippi. Experience the picturesque waterways of the Mississippi and Ohio Rivers aboard the magnificent Queen of the Mississippi. Step back in time to the grand era of paddlewheels as we explore the heartland of America.

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Ohio and Tennessee River Cruises

St. Louis to Cinncinati aboard American Queen
St. Louis to Cinncinati

9-day St. Louis to Cinncinati Mississippi River cruise sailing aboard the American Queen. Experience the history of bourbon and bluegrass, a fine fusion of American icons. The dynamic blend of historic discovery, toe-tapping bluegrass and the finest distilleries on the Bourbon Trail makes this river cruise simply remarkable.

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Cinncinati to St. Louis aboard American Queen
Cinncinati to St. Louisi

9-day Cinncinati to St. Louis river cruise aboard the American Queen. This idyllic journey allows you to experience both the Ohio and Mississippi Rivers. Iconic ports of call on your voyage include Louisville, Kentucky, site of the Kentucky Derby, and Chester, Illinois, hometown of Popeye the Sailorman as well as historic sites like the Pierre Menard House.

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St. Louis - Nashville aboard American Queen
St. Louis - Nashville

9 day St. Louis to Nashville Mississippi River cruise sailing aboard the American Queen. Enjoy nature’s handiwork as the leaves display a myriad of colors. Your journey will take you from the plains of St. Louis through the Tennessee hills surrounding Nashville.

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Nashville to Chattanooga aboard American Queen
Nashville to Chattanooga

9 day Nashville to Chattanooga river cruise aboard the American Queen. Journey through ports of call that played a part in the conflict which tore a nation apart. Visit fascinating landmarks like Pope’s Tavern Museum in Florence, Alabama that served as a stagecoach stop and hospital for both Confederate and Union forces during the Civil War. As you pass through gracious towns and encounter the welcoming people that inhabit them, you’ll gain a new appreciation for how the fabric of America has been woven back together.

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Chattanooga to Nashville aboard American Queen
Chattanooga to Nashville

9 day Chattanooga to Nashville Mississippi River cruise sailing aboard the American Queen. America has given rise to many forms of music but few are recognized as being more quintessentially homegrown than country music. Country music is more popular than ever, and this cruise takes you right to Nashville, Music City and home of the Grand Ole Opry.

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Nashville to Memphis aboard American Queen
Nashville to Memphis

9 day Nashville to Memphis Mississippi River cruise sailing aboard the American Queen. Enjoy two popular forms of American music that have more in common than you might think. Begin in the Home of Country Music, Nashville, Tennessee before enjoying a leisurely cruise. Your days will be filled with included shore excursions and your nights will be filled with outstanding country and blues performances. Your cruise concludes in Memphis, Tennessee, Home of the Blues.

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Upper Mississippi River Cruises

St. Louis to St. Paul aboard American Queen
St. Louis to St. Paul

9 day St. Louis to St. Paul - Mississippi River Cruise aboard the American Queen. There’s no better place to begin a journey through America’s Heartland. On your voyage, discover the true inspiration behind Mark Twain’s beloved American classics in his hometown of Hannibal.

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St. Paul to St. Louis aboard American Queen
St. Paul to St. Louis

9 day St. Paul to St. Louis - Mississippi River Cruise aboard the American Queen. Journey back to a time when anything seemed possible. From the scenic bluffs of Red Wing, Minnesota to St. Louis, Missouri's expansive and bustling Union Station marketplace, you'll experience the American spirit, generosity and creative independence.

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Roundtrip St. Paul aboard American Queen
Roundtrip St. Paul

9 day Roundtrip St. Paul Mississippi River cruise aboard the American Queen. Join us on a nostalgic journey to the fun-loving, carefree days of the 50s and 60s as we re-create the music, activities and events of this golden era. You’ll rock around the clock to the sounds of Motown and legendary artists like Chuck Berry and Fats Domino.

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Roundtrip St. Louis aboard American Queen
Roundtrip St. Louis

9 day Roundtrip St. Louis Mississippi River cruise aboard the American Queen. Visit Mark Twain’s hometown of Hannibal, Missouri from where much of his inspiration for his stories of Tom Sawyer and Huckleberry Finn is derived. Witness his words and wit brought to life by an expert tribute artist. You won’t want to miss this opportunity to share the Mississippi River with Mark Twain.

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St. Paul to St. Louis aboard Queen of the Mississippi
St. Paul to St. Louis aboard Queen of the Mississippi

8 day, 7 night Mississippi River cruise from St. Louis to St. Paul, aboard the greatest paddlewheeler to ever grace the Mississippi River, the Queen of the Mississippi. Journey through America’s Heartland from tranquil towns and bustling cities to impressive locks and dams. Adventure is around every corner whether you choose to pilot a river barge at the Dubuque’s Mississippi River Museum, dance to Scandinavian folk tunes at the Norwegian Heritage Center in La Crosse, or explore the heart of Amish Country.

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